Down's Syndrome...

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28 Aug 2014 08:00 #157605 by Edan
Replied by Edan on topic Down's Syndrome...

Whyte Horse wrote: I want to ask what the significance of Down's syndrome is? I mean is it a flaw? Or maybe some kind of gene expression that is more fit to survive?


Don't quote me on this, but I believe the higher increase in Down's babies is to do with the age of the parents. The older the parents, the more likely they are have to children with it.

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28 Aug 2014 12:39 #157616 by ren
Replied by ren on topic Down's Syndrome...
Down's syndrome is a trisomy and is most often caused by a faulty egg. While the gamete precursors are created at the fetal stage for women and stored longterm, they only become proper gametes once they've been expulsed for fertilisation (final separation happens . As Edan says, with age, these cells fail to separate properly before fertilisation, this results in trisomies, which sometimes survive.

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29 Aug 2014 03:45 #157700 by Whyte Horse
Replied by Whyte Horse on topic Down's Syndrome...
So it sounds like an aging population phenomenon

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